A mysterious potion switches the personalities of a buttoned up doctor and his laid back son.

To stop an elusive criminal, a maverick detective enlists the aid of a police dog who's an unusually intelligent smart alec.

Karma comes into play when a wealthy wisecracking landlord is ordered by a court to live in the filthy building that he runs.

Beethoven, the St. Bernard dog, becomes a father, but his girlfriend Missy is dognapped, and his puppies are in danger of the same fate.