Mickey and all his friends hold their own Christmas party at the House of Mouse, after being snowed in.

When villains come to Mickey's House of Mouse, he and his friends attempt to keep the show running.

Stitch, an alien living on Earth disguised as a dog with his human family, continues his adventures when he discovers that the alien family he never knew he had is now in Hawaii, being hunted down by galactic forces.

New circumstances forces Lilo and her alien friends to part ways while Gantu and Dr. Van Hamsterviel create the Stitch clone, Leroy, in order to capture all of the experiments and take over the galaxy.