The story of the relationship between Karamakate, an Amazonian shaman and last survivor of his people, and two scientists who work together over the course of forty years to search the Amazon for a sacred healing plant.

Zoe finds the best flavor for a big coffee and donuts chain, but the story needs to be better than: invented in a lab with a test group. She's sent to Colombia to get a story. She meets Diego, a single coffee farmer.