Barbara O'Brien, an Irish Catholic mother, has her life turned upside-down when her son, a freshman in college, is involved in a tragic hazing incident.

In Colombia, a young surfer meets the woman of his dreams - and then meets her uncle, Pablo Escobar.

As a young New York City couple goes from college romance to marriage and the birth of their first child, the unexpected twists of their journey create reverberations that echo over continents and through lifetimes.