In a post-apocalyptic plague-ridden world, a man and woman face unimaginable horrors when he suddenly becomes infected, and the only possible cure slowly drives him mad.

An altruistic doctor (Natali Yura) and cocky treasure hunters (Randy Couture) and (Chuck Zito) must join forces to uncover the Mayan legend of the White Witch.

A young woman is held captive in an underground medical facility where selected individuals are perpetually mutilated and then healed using a secret Antidote.