Over the course of a decade, a young woman becomes increasingly dysfunctional due to undiagnosed mental illness, or perhaps to drugs, while her more stable friend sometimes tries to help, sometimes backs away to preserve herself.

When a brother accompanies his estranged sister on a road trip, they rediscover how obnoxious they are together - and how much they might need each other.

After undergoing facial-reconstructive surgery, Edward becomes fixated on an actor in a stage production based on his former life.