A young girl is destined to liberate her world from the grip of the Magisterium which represses people's ties to magic and their animal spirits known as daemons.

In a future where mutants are nearly extinct, an elderly and weary Logan leads a quiet life. But when Laura, a mutant child pursued by scientists, comes to him for help, he must get her to safety.

Deadpool is offered a place in the Marvel Cinematic Universe by the Time Variance Authority, but instead recruits a variant of Wolverine to save his universe from extinction.