As Alyssa and Karla try to escape from the church home that holds them captive, Karla is slaughtered by a vicious, semi-human creature.

To foil a terrorist plot, an FBI agent undergoes facial transplant surgery to assume the identity of the criminal mastermind who murdered his only son, but the criminal wakes up prematurely and seeks revenge.

A girls' weekend away turns into a nightmare when, one by one, they are killed by their own vanity.