The true story of the U.S. Government's 1932 Tuskegee Syphilis Experiment, in which a group of black test subjects were allowed to die, despite a cure having been developed.

Shakes is good at his job as party clown - when he's sober and shows up. Five druggy clowns frame him for the murder of his boss.

About Charlie Jones, a washed up, ex major league ballplayer, and how he gets a second chance at life and love by managing a Jewish, orthodox yeshiva baseball team.