After the events of Spiders (2000), a scientist conducts genetic tests, and a couple becomes the perfect host. Now, the hunt is on, as an army of arachnids is after the succulent human flesh. Who can stop the spiders' feeding frenzy?

Shakes is good at his job as party clown - when he's sober and shows up. Five druggy clowns frame him for the murder of his boss.