A scientist and a teacher living in a dystopian future embark on a journey of survival with a special young girl named Melanie.

The unlikely friendship that kindles between a struggling stand-up comedian from L.A., forced to move back home with his tail between his legs, and a tragically flawed, but charming and charismatic, alcoholic dermatologist.

Optimistic Jasper Cates and gloomy Callie Morgan initially clash, but grow closer while waiting desperately for life-saving transplant organs in a specialized university hospital ward. Finally they get them, actually from the same...