Lisbeth is recovering in a hospital and awaiting trial for three murders when she is released. Mikael must prove her innocence, but Lisbeth must be willing to share the details of her sordid experiences with the court.

As computer hacker Lisbeth and journalist Mikael investigate a sex-trafficking ring, Lisbeth is accused of three murders, causing her to go on the run while Mikael works to clear her name.