In the early 1960s, CIA agent Napoleon Solo and KGB operative Illya Kuryakin participate in a joint mission against a mysterious criminal organization, which is working to proliferate nuclear weapons.

Non-linearly follows two kids, rejected by their peers, who become friends. They separate later in life and dedicate to their careers. Still, they feel as if something is missing.

Beth is a young, ambitious New Yorker who is completely unlucky in love. However, on a whirlwind trip to Rome, she impulsively steals some coins from a reputed fountain of love, and is then aggressively pursued by a band of suitors.

A doctor travels to a remote plantation to care for a disturbed boy who has inexplicable abilities. She ignites a war of science versus religion with the local priest who believes the boy is possessed by the Devil.