A genetically engineered dog escapes from the science facility where it was created. A family takes it in unaware of its deadly instincts which soon emerge. The scientist who created the dog tries to find it before its too late.

In Missouri, during the 1840s, young Huck Finn fearful of his drunkard father and yearning for adventure, leaves his foster family and joins with runaway slave Jim in a voyage down the Mississippi River toward slavery free states.

With her life at a crossroads, 25 year old Sophie Conway returns home to the small town she always wanted to forget. Once home, she is faced with the friends and lovers she left behind, a tangled relationship with her Mother, and ...