A group of ghost hunters must up their game to compete in the competitive world of paranormal TV shows, leading them to a truly haunted prison with a grisly past that proves to be more than they bargained for.

The Turtles and the Shredder battle once again, this time for the last canister of the ooze that created the Turtles, with which Shredder wants to unleash an army of new mutants.