In a post-zombie world, where the infected live normal lives, their retroviral drug is running out.

It follows a college student as she boards a party train for Halloween, and ends up fighting for her life when a mysterious assailant begins killing the people one-by-one.

Inspired by True Events: A young woman who unknowingly grew up in federal witness protection reels after her mother's murder, leading her to question everything that she thinks is true.

The remaining survivors are coerced to take a New Year's Eve redemption ride on the very same train, where a new evil awaits and the terrified passengers must once again fight to survive the ride.