Marie is a vampire with a thirst for bad guys. When she fails to properly dispose of one of her victims, a violent mob boss, she bites off more than she can chew and faces a new, immortal danger.

An FBI undercover agent infiltrates the mob and finds himself identifying more with the mafia life, at the expense of his regular one.

The seemingly random killings of an assassin puzzle her former lover, a wealthy Greek crime boss whose organization is jeopardized by his love for her, and the detective following her rising body count.