The Bride continues her quest of vengeance against her former boss and lover Bill, the reclusive bouncer Budd, and the treacherous, one-eyed Elle.

The Bride must kill her ex-boss and lover Bill who betrayed her at her wedding rehearsal, shot her in the head and took away her unborn daughter. But first, she must make the other four members of the Deadly Viper Assassination Squad

An American nurse living and working in Tokyo is exposed to a mysterious supernatural curse, one that locks a person in a powerful rage before claiming their life and spreading to another victim.