Security guard David Dunn uses his supernatural abilities to track Kevin Wendell Crumb, a disturbed man who has twenty-four personalities.

When a short-tempered mobster and his gang of thugs try to shake down a neighborhood bar, they're soon confronted with the wrath of its owner - a mysterious southern mother with a dangerous past.

Two corrupt cops set out to blackmail and frame every criminal unfortunate enough to cross their path. Events, however, are complicated by the arrival of someone who appears to be even more dangerous than they are.

Jane experiences romance, comedy, tragedy, and crises as imagined by eight different filmmakers.