Renato, a Mexican aviation exec, is shocked to learn he has an American half-brother he never knew about, the free-spirited Asher. They are forced on a road trip together, tracing the path their father took from Mexico to the US.

Father-to-be Alan is shocked to learn that he was born a sextuplet. With his newfound brother Russell riding shotgun, the duo sets out on a hilarious journey to reunite with their remaining long-lost siblings.

A truck driver has been forced to smuggle illicit cargo to save her brother from a deadly prison gang. With FBI operatives hot on her trail, Sally's conscience is challenged when the final package turns out to be a teenage girl.