Renato, a Mexican aviation exec, is shocked to learn he has an American half-brother he never knew about, the free-spirited Asher. They are forced on a road trip together, tracing the path their father took from Mexico to the US.

While visiting their getaway cabin, five friends succumb to a flesh-eating disease.

A former Marine and his old war buddy face off against the Mexican cartel behind the disappearance of his daughter.